P-Cresyl sulfate (pCS)

P-Cresyl sulfate (pCS)

Manufacturer : “TINESH MANUFACTURING ENTERPRISES PVT LTD Address: Plot No. 251 To 264, Jai Radhey Industrial Estate, Near Railway Ove, Surat – 394230, Gujarat,lndia ”

 CAS Number :  91978-69-7

para-Cresol sulfate. Molecular Formula: C7H7O4S. K. Formula Weight: 226.3.
Storage: Storage: -20°C
Product Description: Biological and Biochemical prototype protein-bound uremic toxin. / Formulation: A solid
Formal Name: sulfuric acid, mono(4-methylphenyl) ester, monopotassium salt
Purity: ≥95%
Formula Markup: C7H7O4S • K
Formula Weight: 226,3
Shelf life (days): 1460
CAS Number: 91978-69-7
Notes: p-Cresol sulfate is a sulfate conjugate of the uremic toxin p-cresol, which is formed by bacterial fermentation of proteins in the large intestine.{45960,45961} p-Cresol sulfate increases migration and proliferation of isolated rat aortic vascular smooth muscle cells (VSMCs) when used at a concentration of 500 µM.{45962} It also increases the area of aortic atherosclerotic plaques in nephrectomized ApoE-/- mice fed a high-fat diet when administered at a dose of 100 mg/kg per day via the drinking water. Serum levels of total and free p-cresol sulfate are increased in patients with advanced stage chronic kidney disease and positively associated with vascular calcification.{45963}