{"id":1240,"date":"2026-08-23T01:26:54","date_gmt":"2026-08-23T01:26:54","guid":{"rendered":"https:\/\/telematiquechemicalsmarketplace.co\/?post_type=product&p=1240"},"modified":"2026-08-23T01:27:03","modified_gmt":"2026-08-23T01:27:03","slug":"jwh-018china_js-pc","status":"publish","type":"product","link":"https:\/\/telematiquechemicalsmarketplace.co\/?product=jwh-018china_js-pc","title":{"rendered":"JWH-018(China_JS-PC)"},"content":{"rendered":"

MANUFACTURER<\/strong><\/p>\n

Jiangsu Pharmaceutical Co., Ltd.
\nAddress: 5th, 8th, 10th, 11th and 15th floors, Jinying Building, No. 258, Zhongyang Road, Xuanwu District, Nanjing City
\nPostal code: 210009<\/p>\n

JWH-018(China_JS-PC) (CAS Num 209414-07-3)<\/strong><\/p>\n

JWH-018 is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB\u2081 and CB\u2082 cannabinoid receptors, with some selectivity for CB\u2082.
\nFormula: C24H23NO
\nMolar mass: 341.45 g\/mol
\nRoutes of administration: Smoked, Oral<\/p>\n

JWH-018 produces effects in animals similar to those of tetrahydrocannabinol (THC), a cannabinoid naturally present in cannabis, leading to its use in synthetic cannabis products that in some countries are sold legally as \u201cincense blends\u201d.\/ JWH-018 is a synthetic cannabinoid receptor agonist with a strong affinity for the CB1 and CB2 receptors (EC50 = 102 nM and 133 nM, respectively)1. Binding to the receptors triggers a reduction of intracellular cAMP levels by inhibition of adenylate cyclase. In vivo studies on experimental mouse models showed similar responses as THC, including hypothermia, catalepsy, and hypolocomotor effects2.
\nIn vitro, JWH-018 impaired electrically-induced synaptic transmission as well as LTP and glutamate\/GABA release in ex vivo hippocampal slices. All behavioural and neurochemical effects could be prevented by pre-treatment with a CB1 receptor antagonist3.<\/p>\n","protected":false},"excerpt":{"rendered":"

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\nPaypal Transfer (8% charges extra on invoice amount as Paypal transaction charges)<\/p>\n<\/div>\n

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